Tim Anderson homered in a three-run fifth inning, and the White Sox went on to a 5-3 victory over the Tigers on Saturday night at Comerica Park.
Anderson went 1-for-4, lowering his American League-leading average to .335, but the one hit was a no-doubter of a home run to left.
Ivan Nova (11-12) allowed two runs and eight hits in five innings and three Sox relievers finished. Alex Colome gave up a run in the ninth but held on for his 29th save in 31 chances.
Anderson opened the scoring with his 18th home run, a solo shot off Tyler Alexander (1-4). The inning only got worse for the left-hander: After singles by Jose Abreu and Eloy Jimenez, Yoan Moncada hit a two-run triple.
The Tigers answered with two runs in the fifth. Victor Reyes hit an RBI groundout, and Brandon Dixon followed with an unusual sacrifice fly to first baseman Jose Abreu. Willi Castro tagged up from third and scored when Abreu caught a popup in foul ground and tumbled into the stands.
Abreu hit a two-run single in the eighth to push the Chicago lead back to three. He leads the AL with 121 RBIs.
